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Recent accomplishments

Structural and biochemical studies on folate-dependent tRNA methyltransferase (TrmFO)

Discovery of multi-site specific tRNA methyltransferase (Trm1) and its structural and functional studies

Biophysical studies on knotted tRNA methyltransferase (TrmH) and clarification of its physiological function

Discovery of the tRNA modified nucleotides and modification enzyme network

Structural and functional studies on novel tRNA splicing endonucleases